#1
To determine the impact of menopause and diabetes on vasoregulatory and inflammatory processes – to analyze vasoactive disorders (endothelial dysfunction, contractility changes, flow changes, innervation disorders) and their connection with inflammation and metabolic abnormalities.
#2
To analyze pathological versus compensatory action of sulfide signaling pathway with regard to the role of perivascular adipose tissue and renin-angiotensin system.
#3
To verify the beneficial effect of natural H2S donor on vasoactive, metabolic and inflammatory processes in vascular wall and perivascular adipose tissue.
#4
To analyze H2S production within cardiovascular system and in plasma with regard to reproductive status and treatment.
